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Shin Psychedelics Sabbin Antidepressants ne?

Written by edita

Rikicin damuwa shine mafi yawan cututtukan tabin hankali a Amurka, yana shafar kusan manya miliyan 40 kowace shekara, kuma duk da yawan magungunan rage damuwa da ake samu, juriyar jiyya na faruwa a kusan kashi 30% na marasa lafiya. Rashin damuwa yana da tasiri mai mahimmanci na tattalin arziki akan tsarin kiwon lafiyar Amurka, yana kashe tsakanin dala biliyan 42.3 zuwa dala biliyan 46.6 a kowace shekara, ma'ana yana da mahimmanci a nemo madadin hanyoyin magani. Sa'ar al'amarin shine, sabon bincike ya nuna cewa psychedelics na iya zama amsar. Sakamakon gwaji na asibiti ya nuna cewa psilocybin, mai karfi mai kwakwalwa, yana da tasirin antidepressant a cikin marasa lafiya da ciki kuma ya fi tasiri fiye da escitalopram. Tabbas, wannan ɗaya ne kawai daga cikin yawancin binciken da aka yi nasara wanda ya shafi amfani da masu tabin hankali a matsayin maganin tabin hankali.

Cybin Inc yana mai da hankali kan haɓaka masu ilimin halin ɗan adam zuwa hanyoyin warkewa ta hanyar ƙirƙira dandamali na gano magunguna, sabbin tsarin isar da magunguna, sabbin hanyoyin ƙirƙira da tsarin jiyya don rashin lafiyar hankali.

A ranar 13 ga Afrilu, Cybin ya sanar da tabbataccen bayanai na asali na CYB004 daga nazarin pharmacokinetic da ke kimanta kwayar halittar dimethyltryptamine (DMT), CYB004, wanda ake gudanarwa ta hanyar inhalation. Musamman, inhaled CYB004 ya nuna fa'idodi masu mahimmanci sama da DMT na ciki da kuma inhaled, gami da tsawon lokaci na aiki da ingantacciyar rayuwa. Har ila yau, binciken ya nuna cewa CYB004 da aka shayar da shi yana da irin wannan tasirin tasiri da bayanin martaba zuwa IV DMT. Waɗannan bayanan na iya goyan bayan yuwuwar iskar shaka a matsayin tsarin isarwa mai inganci da kulawa mai kyau don masu tabin hankali. A halin yanzu Cybin yana haɓaka CYB004 don magance matsalolin tashin hankali. Kamfanin yana sa ran shigar da tsarin shigar da doka don nazarin matukin jirgi a cikin kwata na biyu na 2022 da kuma fara binciken matukin jirgi a cikin kwata na uku.

"A yawancin karatu, DMT ya nuna ya zama mai ban sha'awa da tasiri mai tasiri don magance matsalolin lafiyar kwakwalwa. Koyaya, sanannun illolin kamar rashin tunani da damuwa da yanayin gudanarwar sa sun hana amfani da samu a tarihi a tarihi. CYB004 ta hanyar inhalation na iya magance waɗannan ƙalubalen kuma a ƙarshe yana goyan bayan hanyar asibiti gaba don wannan muhimmin magani. A matsayin wani ɓangare na manufar Cybin gabaɗaya don ƙirƙirar amintattun hanyoyin kwantar da hankali na tushen tabin hankali, ana haɓaka CYB004 inhaled don yuwuwar shawo kan iyakokin IV DMT kuma ya zama zaɓin magani mai mahimmanci don rikicewar damuwa ga marasa lafiya da likitoci, ”in ji Doug Drysdale, Shugaba na Cybin. .

A ranar 8 ga Afrilu, Cybin ya ba da sanarwar buga wani aikace-aikacen haƙƙin mallaka na ƙasa da ƙasa wanda ke rufe hanyoyin isar da iskar shaka don ƙwayoyin mahaukata da yawa, yana ƙara ƙarfafa matsayin Cybin ta hankali (IP). Aikace-aikacen PCT zai ba da damar Cybin don neman kariya ta IP don nau'o'in nau'i na nau'i na nau'i na nau'i na nau'i na nau'i na kwakwalwa wanda a halin yanzu ana bincike da haɓaka ta kamfanin da kuma sauran kwayoyin halitta masu kwakwalwa waɗanda za a iya haɓaka a nan gaba.

"Buga wannan aikace-aikacen haƙƙin mallaka na PCT yana nuna ci gaba da sadaukar da kai don ganowa da haɓaka sabbin hanyoyin magance cutar hauka, ban da ganowa da haɗa hanyoyin da za a iya ingantawa da ingantaccen tsarin bayarwa tare da waɗannan 'yan takarar na asibiti," in ji Doug Drysdale. "Bugu da ƙari, ci gabanmu don tabbatar da IP don hanyoyin isar da hankali na musamman yana daidaitawa da goyan bayan shirinmu na yanzu na CYB004 na bututun DMT ta hanyar inhalation, wanda ke da nufin shawo kan wasu sanannun ƙalubalen DMT na baka da IV."

Cybin ta sanar a ranar 31 ga Maris cewa binciken da ta dauki nauyin yi ta amfani da fasahar Kernel Flow ta gudanar da ziyarar karatu ta farko. Babban makasudin binciken shine a kimanta kwarewar ɗan takara sanye da Kernel Flow yayin da yake cikin canjin yanayin wayewa bayan gudanar da ketamine. Mahalarta za su sami ko dai ƙananan ƙwayar ketamine ko placebo yayin da suke sanye da lasifikan kai na Flow, wanda aka sanye da na'urori masu auna firikwensin hi-tech don yin rikodin ayyukan kwakwalwa kuma za su ba da rahoton kwarewar su ta amfani da takaddun tambayoyin da aka tsara da ingantattun ƙima yayin ziyarar binciken da kuma biyo baya. Binciken na mako hudu zai kuma kimanta ayyukan kwakwalwa kafin da kuma bayan gudanar da jami'an binciken - ƙananan ketamine ko placebo.

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edita

Edita a shugaba na eTurboNew ita ce Linda Hohnholz. Ta dogara ne a HQ eTN a Honolulu, Hawaii.

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