Seelos Therapeutics, Inc., wani kamfani ne na likitancin likitanci da ke mayar da hankali kan haɓaka hanyoyin kwantar da hankali don rikice-rikice na tsarin juyayi na tsakiya da cututtukan da ba kasafai ba, a yau ya sanar da cewa ya karɓi wasiƙar amincewa ta Sanarwar Gwajin Clinical (CTN) daga Sashen Lafiya na Gwamnatin Ostiraliya. Gudanar da Kaya na Therapeutic (TGA) don nazarin matukin jirgi na SLS-005 ( allurar trehalose, 90.5 mg / mL don jiko na cikin jini) don kula da marasa lafiya da cutar Alzheimer.
"Ayyukan Trehalose a cikin cutar Alzheimer na musamman ne saboda yana hana duka cututtukan cututtukan beta-amyloid da tau aggregates a cikin ƙirar rodent na asali. Wannan aikin yana bayyana a cikin intraneuronal, yana faruwa a cikin tantanin halitta, wanda ya bambanta da magungunan da aka mayar da hankali ga antibody. Dukansu furotin na amyloid precursor da tau oligomers sune cytoplasmic a cikin tantanin halitta kuma Trehalose na iya aiwatar da su ta hanyar haifar da autophagy da tsarin proteasomal. Autophagy yana da hannu wajen lalata sauran tarin furotin da ba su da kyau, "in ji Raj Mehra Ph.D., Shugaba da Shugaba na Seelos. "Muna sa ran samun shaida da mahimman bayanai game da dacewa da SLS-005 a cikin kula da waɗannan yanayin jijiyoyin jiki, waɗanda ke da illa ta jiki, da motsin rai da kuma rashin kuɗi ga marasa lafiya da danginsu."
Bugu da ƙari, Seelos ya sami izini don gudanar da binciken kwando na daban (ACTRN: 12621001755820) a Ostiraliya don kimanta tasirin SLS-005 akan ci gaba da cututtuka da tsanani, da aminci da haƙuri, a cikin mahalarta tare da zaɓaɓɓen cututtuka na neurodegenerative. ciki har da cutar Huntington.
Hukumar Ostiraliya ta Ostiraliya don gwaje-gwajen asibiti, TGA, da Cibiyar Bincike da Ƙarfafa Harajin Gwamnatin Ostiraliya suna ba da dama mai ban sha'awa ga ƙananan kamfanonin fasahar kere-kere na Amurka don fara gwajin asibiti a Ostiraliya a ƙoƙarin haɓaka ƙaddamar da karatu da amfani da ƙaƙƙarfan asibiti na ƙasar. damar gwaji.
ABUBUWAN DA ZA KU GUDU DAGA WANNAN LABARI:
- Hukumar Ostiraliya ta Ostiraliya don gwaje-gwajen asibiti, TGA, da Cibiyar Bincike da Ƙarfafa Harajin Gwamnatin Ostiraliya suna ba da dama mai ban sha'awa ga ƙananan kamfanonin fasahar kere-kere na Amurka don fara gwajin asibiti a Ostiraliya a ƙoƙarin haɓaka ƙaddamar da karatu da amfani da ƙaƙƙarfan asibiti na ƙasar. damar gwaji.
- , Wani kamfani na asibiti na asibiti wanda ya mayar da hankali kan ci gaba da hanyoyin kwantar da hankali ga cututtuka na tsarin juyayi na tsakiya da cututtuka masu wuyar gaske, a yau ya sanar da cewa ya karbi wasiƙar amincewa da Sanarwar Gwaji na Clinical (CTN) daga Ma'aikatar Harkokin Kiwon Lafiya ta Australiya (TGA). ) don nazarin matukin jirgi na SLS-005 ( alluran trehalose, 90.
- 12621001755820) a Ostiraliya don kimanta tasiri na SLS-005 akan ci gaban cuta da tsanani, da aminci da haƙuri, a cikin mahalarta tare da zaɓaɓɓun cututtukan neurodegenerative ciki har da cutar Huntington.
