Masu bincike a Cibiyar Ciwon daji na Nagourney da Metabolomycs, Inc. za su bayar da rahoto a yau a Cibiyar Nazarin Ciwon daji ta Amirka (AACR) Taron Shekara-shekara a New Orleans cewa sun yi annabci game da rayuwar masu ciwon daji na ovarian ta hanyar auna sa hannu na rayuwa a cikin ฦwayar ฦwayar cuta. Sakamakon zai iya ษata gaba a cikin abin da likitocin oncologists zasu iya ฦayyade a gaba yadda majiyyaci zai amsa magani don inganta sakamakon rayuwa.
A cewar masu binciken, ilimin halittar ษan adam ciwon daji yana nuna ci gaba daga al'ada zuwa mummuna canji zuwa juriya na miyagun ฦwayoyi duk abin da ke haifar da sake fasalin tsarin rayuwa na duniya.
"Mun nuna a baya cewa juriya na platinum a cikin cututtukan gynecologic ana annabta ta hanyar sauye-sauye na rayuwa da aka auna a cikin plasma na marasa lafiya a lokacin ganewar asali," in ji Dokta Robert Nagourney, Founder da Medical Director na Nagourney Cancer Institute. "Yanzu muna nuna cewa ฦwayar ฦwayar ฦwayar ฦwayar cuta da aka auna a cikin kafofin watsa labaru na ฦwayar cutar ฦwayar cuta ta mutum ta 1o yana ba da irin wannan fahimta game da amsawar magunguna don maganin platinum."
Ciwon daji na Ovarian shine babban dalilin mutuwar ciwon daji na gynecologic. Yayin da kashi 80 cikin XNUMX na cututtukan ovarian ke amsawa ga maganin platinum, yawancin lokuta sun sake faruwa, kuma marasa lafiya sun mutu a cikin shekaru biyar. Tare da haษaka sha'awar metabolism na ษan adam a matsayin muhimmin sashi na ilimin halittar kansa, wannan rahoto kan ciwon daji na ovarian shine mafi kwanan nan na da yawa daga cikin nazarin ฦungiyar a yawancin cututtukan daji masu ci gaba waษanda ke tabbatar da rawar da metabolomics ke bayarwa wajen tantance rayuwa.
Masu binciken sun gudanar da kididdigar tandem Mass Spectrometry (MS/MS) akan kafofin watsa labarai na al'ada na nama na ciwon daji na ovarian ษan adam don bincika sa hannu na ฦwayar ฦwayar ฦwayar ฦwayar ฦwayar ฦwayar ฦwayar ฦwayar ฦwayar ฦwayar ฦwayar ฦwayar ฦwayar ฦwayar ฦwayar ฦwayar ฦwayar ฦwayar ฦwayar ฦwayar ฦwayar ฦwayar ฦwayar ฦwayar ฦwayar ฦwayar ฦwayar ฦwayar ฦwayar ฦwayar ฦwayar ฦwayar ฦwayar ฦwayar ฦwayar ฦwayar ฦwayar ฦwayar ฦwayar ฦwayar ฦwayar ฦwayar ฦwayar ฦwayar ฦwayar ฦwayar ฦwayar ฦwayar ฦwayar ฦwayar ฦwayar ฦwayar ฦwayar ฦwayar ฦwayar ฦwayar ฦwayar ฦwayar ฦwayar ฦwayar ฦwayar ฦwayar ฦwayar ฦwayar ฦwayar ฦwayar ฦwayar ฦwayar ฦwayar ฦwayar ฦwayar ฦwayar ฦwayar ฦwayar ฦwayar ฦwayar ฦwayar cuta.
Mass Spectrometry da aka gudanar akan kafofin watsa labaru na al'adun nama na marasa lafiya 11 idan aka kwatanta da marasa lafiya 8 waษanda suka sami cikakkiyar gafarar pathologic (pCR) tare da marasa lafiya uku waษanda ke da sauran cututtukan duk sun biyo bayan shigar da chemotherapy tare da Carboplatin da Paclitaxel. Binciken ya haษa da amino acid, amines biogenic, hexoses, phosphatidylcholines, lyso-phosphatidylcholines da sphingomyelins.
"Tare da irin wannan hangen nesa, muna kan gab da tabbatar da mafi kyawun hanyar magani ga wadanda ke da ciwace-ciwacen ovarian," in ji Dokta Nagourney.
