Sabbin Nazari Yana Gano Dalilai da Magani na ɗigon jini mai alaƙa da COVID-19

Ko da yake galibi cutar numfashi ce, an nuna COVID-19 yana haifar da amsoshi iri-iri, gami da illa ga tsarin zuciya da jijiyoyin jini. Wasu marasa lafiya sun nuna amsa mai kumburi wanda zai iya haifar da thrombosis, kuma akwai babban abin da ya faru ga wadanda ke da ciwo mai tsanani.

A cikin takarda ta farko, masu bincike a Jami'ar Pennsylvania sun gano manyan masu shiga tsakani na kumburi da cututtukan zuciya a cikin marasa lafiyar COVID-19 waɗanda ke da alaƙa da inganci tare da kunna platelet a cikin tsarin BioFlux. Ƙungiyar ta kuma nuna cewa Syk inhibitor fostamatinib ya juyar da hyperactivity na platelet a cikin gwaje-gwajen BioFlux. Masu binciken sun kammala cewa wannan yana wakiltar wata keɓantacciyar hanya ce ta sigina don daidaita wannan tasirin.

A cikin takarda na biyu, masu bincike na Jami'ar Tuebingen sun nuna cewa rage yawan matakan cAMP (cyclic adenosine monophosphate) a cikin platelet ya kara yawan kwayar cutar kwayar cutar da kwayar cutar da kuma samuwar thrombus. An hana waɗannan tasirin ta hanyar Iloprost, wani wakili na warkewa wanda aka yarda da shi a asibiti wanda ke haɓaka matakan cAMP na ciki a cikin platelets.

Duk takaddun sun dogara da tsarin BioFlux don tantance aikin platelet a cikin marasa lafiya na COVID-19. Tsarin BioFlux yana aiki azaman "jijiya akan guntu" wanda ke sarrafa daidaitaccen mahalli don kwaikwayi yanayi a cikin jikin ɗan adam, yana samar da ingantaccen dandamali don binciken aikin jini mai alaƙa da COVID-19. An yi amfani da shi a cikin dakunan gwaje-gwaje sama da 500 a duniya, ana samun tsarin BioFlux a cikin jeri iri-iri don saduwa da buƙatun aikace-aikacen kowane dakin gwaje-gwaje. Ana samun tsarin tare da kewayon iyawa da kayan aiki kuma ana amfani da su a cikin bincike na asali ta hanyar gano magunguna da haɓakar bincike.

 

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Shafin Farko