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$100M don Haɓaka Maganin Maganin Ciwon Jiki na Mummunan Cututtuka Masu Ƙarfi.

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Dianthus Therapeutics a yau ta ba da sanarwar kammala tallafin dala miliyan 100 na Series A wanda 5AM Ventures, Abokan Avidity Partners, da Fidelity Management & Research Company ke jagoranta, tare da sa hannun ƙarin masu saka hannun jari ciki har da Wedbush Healthcare Partners da kafa masu saka hannun jari Fairmount, Tellus BioVentures, da Venrock Healthcare Capital Partners. . Za a yi amfani da kuɗin don faɗaɗa jagoranci da ƙungiyoyin kimiyya, haɓaka shirin jagorar kamfanin, DNTH103, zuwa asibiti a wannan shekara, da haɓaka ƙarin shirye-shiryen bututun ganowa ga mutanen da ke fama da cututtuka masu tsanani da ba safai ba. DNTH103 mai ƙarfi ne, na gaba-gaba na rigakafin ƙwayoyin cuta na monoclonal wanda ke zaɓin zaɓin nau'i mai aiki na ƙarin C1s, mai yuwuwar ba da damar ƙaramin ƙarar ƙarar ƙwayar cuta da kuma ƙarancin kulawar ƙwayar cuta wanda ke ƙara haɓaka tare da fasahar haɓaka rabin rayuwa. 

Dianthus ya kuma sanar da nadin Marino Garcia a matsayin Shugaba da Babban Jami'in Gudanarwa, wanda zai shiga cikin Nuwamba 2021, da Simrat Randhawa, MD, MBA, a matsayin Babban Jami'in Lafiya. Mista Garcia, tsohon mai ba da shawara da dabarun, ya kawo fiye da shekaru 25 na ƙwarewar masana'antu a cikin ci gaban kasuwanci da ayyukan jagoranci a manyan kamfanonin fasahar kere-kere da kantin magani, mafi kwanan nan a matsayin Babban Mataimakin Shugaban Kasa, Kasuwanci da Ci gaban Kasuwanci a Zealand Pharma. Dokta Randhawa ya kawo fiye da shekaru 20 na aikin asibiti da ƙwarewar masana'antar harhada magunguna ga Dianthus, gami da manyan ayyuka na jagoranci da aka mayar da hankali a cikin wuraren da ba a san su ba. Kwanan nan ya yi aiki a matsayin Babban Mataimakin Shugaban Kula da Lafiya da Lafiya a Aurinia Pharmaceuticals.

"Mun himmatu wajen inganta rayuwar mutanen da ke fama da matsananciyar cututtuka na autoimmune kuma muna da tabbacin cewa zaɓaɓɓen rigakafinmu na da damar zama mafi kyawun jiyya," in ji Marino Garcia, Shugaba da Babban Jami'in Gudanarwa, Dianthus Therapeutics. "Muna da damar samun ƙwararrun ƙwararrun ƙwararrun masu saka hannun jari na fasahar kere kere, ƙwararrun membobin hukumar, da ƙwararrun shugabanni da masana kimiyya yayin da muke ciyar da ɗan takararmu jagora zuwa asibitin nan gaba a wannan shekara, muna haɓaka bututun bincikenmu, da haɓaka ƙungiyarmu a cikin watanni masu zuwa. . Dianthus yana matsayi don zama jagora, kamfani na gaba na gaba wanda ke jagorantar zurfin fahimtar bukatun marasa lafiya. "

Dianthus yana amfani da ikon zaɓi a cikin hanyoyin da suka dace don ƙirƙirar ƙwayoyin rigakafi masu ƙarfi na monoclonal tare da yuwuwar shawo kan iyakokin hanyoyin warkewa na yanzu. Ba kamar hanyoyin kwantar da hankali na yanzu waɗanda ke ɗaure ga duka sunadaran da ba su da aiki da masu aiki, DNTH103 zaɓen suna yin niyya ne kawai nau'i mai aiki na C1s da ke haɓaka furotin, yana ba da damar ƙarar ƙarar allurai da ƙarancin gudanarwa akai-akai. Fasaha ta tsawaita rabin rayuwa kuma tana ƙara rage yawan adadin kuzari. Tare da waɗannan bambance-bambancen halayen da babban hanawa na C1s, DNTH103 an tsara shi don sauke nauyin babban girma, gudanarwa akai-akai tare da infusions na IV ko rashin dacewa, akai-akai subcutaneous dosing. Haɓaka haɓakar ingantaccen magani na subcutaneous zai iya zama mai canzawa a cikin faɗaɗa yuwuwar yawan majinyata waɗanda za su iya amfana daga ƙarin hanyoyin kwantar da hankali, yayin da rage rashin jin daɗi da rushewar da ke mamaye rayuwar marasa lafiya a yau - a ƙarshe yana ba da damar ƙarin marasa lafiya su rayu cikin koshin lafiya. m. 

"Muna alfaharin tallafawa Dianthus Therapeutics don haɓaka ganowa da ci gaban ƙarni na gaba, mai ƙarfi, da bambance-bambancen rigakafin cututtukan da suka dace," in ji Paula Soteropoulos, Daraktan Hukumar Dianthus da Mai ba da Shawarar Dabarun zuwa 5AM Ventures. "Tare da jagorancin shugaban da aka nada kwanan nan kuma Shugaba Marino Garcia, da ƙwararrun ƙwararrun shugabannin masana'antar fasahar kere kere da kuma 'yan kasuwa waɗanda ke da tarihin nasara, muna fatan ganin Dianthus ya kawo sabbin hanyoyin kwantar da hankali ga marasa lafiya da ke fama da matsananciyar wahala. cututtuka na autoimmune."

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edita

Edita a shugaba na eTurboNew ita ce Linda Hohnholz. Ta dogara ne a HQ eTN a Honolulu, Hawaii.

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